Introduction: Pseudomyxoma peritonei is a rare pathology requiring, according to international recommendations, multidisciplinary management in a specialized center. The aim of our work was to assess the difficulties of this care in our context through the analysis of two cases managed in Ouagadougou. Observations: In the first observation, this was a 60-year-old, male patient, who was diagnosed with a pseudomyxoma peritonei grade I according to the WHO two years after the onset of symptoms. He benefited from cytoreductive surgery and two sessions of adjuvant chemotherapy. Due to lack of sufficient financial resources, he had to interrupt his chemotherapy and died in 2023. For the second observation, it was a 51-year-old, female patient, where the diagnosis of pseudomyxoma peritonei secondary to ovarian and appendicular mucinous cystadeno-carcinoma was retained five months after the onset of symptoms. She underwent cytoreductive surgery with oophorectomy, appendectomy, hysterectomy removing the left ovary and adjuvant chemotherapy courses. The development has been favorable. Conclusion: Pseudomyxoma peritonei remains a very rare pathology in our context, often with diagnostic delay and treatment difficulties. They could be somewhat attenuated by establishing a framework for reflection and management of this type of pathology adapted to our realities.

Africa, Ascites, Ouagadougou, Burkina Faso, Pseudomyxoma Peritonei