Evaluation of carotid intima-media thickness in maintenance hemodialysis patients in Dakar
- Advancements in journal of Urology and Nephrology , 7 (1) : 1-7
Résumé
Objective: To evaluate carotid intima-media thickness (CIMT) and its association with cardiovascular risk factors (CVRFs) in chronic hemodialysis patients. Patients and methods: This cross-sectional study was conducted over a period of six months at the hemodialysis unit of University Hospital Aristide Le Dante in Dakar, Senegal. CIMT was measured using a B mode ultrasonography. Results: Fifty-seven patients, with a mean age of 48.3614.93 years, 42.1% male, were included. The sex ratio was 0.72%. The mean CIMT was 0.835#0.21 mm. Increased CIMT was associated with older age (p=0.004), history of smoking (p=0.034), peripheral artery disease (p=0.02), and elevated pre- and post-dialysis systolic blood pressure and pulse pressure (p<0.05 for all). No association was found with dyslipidemia, C-reactive protein (CRP), phosphate, or intact parathyroid hormone (it) levels. Conclusion: CIMT is a marker of subclinical atherosclerosis in hemodialysis patient. It may help in cardiovascular risk stratification, particularly in older patients, smokers and those with a history of PAD, or elevated blood pressure.
Mots-clés
Carotid Intima-Media Thickness, Atherosclerosis, Hemodialysis, Senegal