ARTICLE
Prevalence and Antimicrobial Resistance of Mycoplasma genitalium Infection Among Women Living With Human Immunodeficiency Virus in South Africa: A Prospective Cohort Study
- Clinical Infectious Diseases , 69 : 873-876
Lien de l'article :
https://doi.org/10.1093/cid/ciz045
Discipline :
Sciences biologiques
Auteur(s) :
Jason J. Ong, Mahlape P. Mahlangu, Admire T Chikandiwa, Helen A. Kelly, Marie-Noelle Didelot, Etienne E. Müller, Venessa Maseko, Michel Segondy, Sinead Delany‐Moretlwe, Ranmini S. Kularatne, Philippe Mayaud, Admire T Chikandiwa, Ewaldé Cutler, Sinéad Delany‐Moretlwe, David A. Lewis, Mahlape Precious Magooa, V Maseko, Pam Michelow, Batanayi Muzah, Tanvier Omar, Adrian J. Puren, Florencia Wendkuuni Djigma, J.-Y. Drabo, Olga Goumbri-Lompo, Nicolas Méda, Bernard Sawadogo, Jacques Simporè, Albert Théophane Yonli, Souleymane Zan, V Costes, M-N Didelot, Sylviane Doutre, Nicolas Leventoux, Nicolas Nagot, Jean Ngou, Michel Segondy, A Devine, Clare Gilham, L Gibson, Helen A. Kelly, Rosa Legood, Philippe Mayaud, Helen Anne Weiss
Auteur(s) tagués :
DJIGMA Wendkuuni Florencia
Renseignée par : DJIGMA Wendkuuni Florencia
Résumé
This prospective cohort study of 622 women living with human immunodeficiency virus (HIV) from Johannesburg (2012) detected Mycoplasma genitalium in 7.4% (95% confidence interval [CI]: 5.5-9.7, 46/622), with detection more likely with lower CD4 counts(adjusted odds ratio [AOR] 1.02 per 10 cells/μL decrease, 95% CI: 1.00-1.03) and higher plasma HIV-1 RNA (AOR 1.15 per log copies/mL increase, 95% CI: 1.03-1.27). No mutations for macrolide/quinolone resistance was detected.
Mots-clés
Mycoplasma genitalium, HIV coinfection, women, prevalence, antimicrobial resistance, CD4 count, HIV-1 viral load, macrolide resistance, quinolone resistance, sexually transmitted infections