Publications (454)
ARTICLE
Plasma chitotriosidase activity in beta-thalassemia major: a comparative study between Sicilian and Sardinian patients
R. Barone, G. Bertrand, J. Simporè, M. Malaguarnera, S. Musumeci
Background: Chitotriosidase is a functional chitinase secreted by activated macrophages, which is extremely increased in plasma of patients with Gaucher disease (beta-glucocerebrosidase deficiency). Recently, we found that chitotriosidase plasma levels were increased to a variable extent in Sicilian patients with beta-thalassemia major. The ai(...)
chitotriosidase, bêta-thalassémie majeure, surcharge en fer, macrophages activés, Sicile, Sardaigne, activité enzymatique plasmatique, étude comparative, pathologie hématologique
ARTICLE
HLA class I in three West African ethnic groups: genetic distances from sub-Saharan and Caucasoid populations
D. Modiano, G. Luoni, V. Petrarca, B. Sodiomon Sirima, M. De Luca, J. Simporé, M. Coluzzi, J. G. Bodmer, G. Modiano
Fulani of Burkina Faso (West Africa) are a particularly interesting ethnic group because of their lower susceptibility to Plasmodium falciparum malaria as compared to sympatric populations, Mossi and Rimaibé. Moreover, the occurrence of a Caucasoid component in their genetic make-up has been suggested on the basis of their physical traits and(...)
HLA classe I, Fulani, Mossi, Rimaibé, Burkina Faso, résistance au paludisme, distance génétique, Plasmodium falciparum, ethnogénétique, ARMS-PCR
ARTICLE
Plasma homocysteine concentrations in a healthy population living in Burkina Faso
Jacques Simporè, Salvatore Pignatelli, Sergio Barlati, Mariano Malaguarnera, Salvatore Musumeci
Background: The low circulating levels of homocysteine observed in a South African black population have been associated with a low occurrence of coronary heart disease.
Objective: The aim of this study was to determine whether the observation of reduced homocysteine levels in South African black subjects is valid in a black population living(...)
homocysteine, cysteine, Burkina Faso, cardiovascular risk, diet, ethnic differences
ARTICLE
Effectiveness of forced rehydration and early re-feeding in the treatment of acute diarrhoea in a tropical area
S. Pignatelli, J. Simporè, M. Ruggieri, S. Musumeci
Background: The administration of oral re-hydration solution (ORS) via continuous infusion through a nasogastric (NG) tube and early refeeding facilitates delivery in hospitalised children and the return back home.
Design: the observation was made during a one-year stage in the Camillian Medical Centre (CMC) of Ouagadougou in Burkina Faso.(...)
diarrhée aiguë, réhydratation forcée, alimentation précoce, réhydratation orale, nasogastrique, enfants, Burkina Faso, médecine tropicale, traitement de la déshydratation