Publications (1733)
ARTICLE
Plasma proteomic profiling reveals distinct protein signatures associated with hepatocellular carcinoma in chronic hepatitis B infection
Sidnooma Véronique Zongo, Michael A Bauer, Lassina Traore, Tegwinde Rebeca Compaore, Albert Théophane Yonli, Augustin Tozoula Bambara, Palwendé Romuald Boua, Roger Arsène Sombié, Oumar Barro, Sosthene K Somda, Mahamoudou Sanou, Jeremy James Martinson, Jean Christopher Chamcheu, Lewis R Roberts, Mitesh J Borad, Bolni Marius Nagalo, Alan J Tackett, Adama Sanou, Florencia Wendkuuni Djigma, Jacques Simpore
Background
Chronic hepatitis B virus (HBV) infection is a leading cause of hepatocellular carcinoma (HCC), yet reliable biomarkers for early detection and risk stratification remain limited. This study aimed to identify plasma proteins associated with disease progression from chronic HBV infection to HCC.
Methods
Plasma proteomic profilin(...)
Hepatocellular carcinoma; Chronic hepatitis B; Cirrhosis; Plasma; proteomics; Biomarkers; Early detection
ARTICLE
Transfusion Safety in Burkina Faso: Molecular and Serological Characterization of VAH and VHB and Coinfections in Blood Donors at the Regional Blood Transfusion Center of Koudougou, Nando Region
Tao, I., Thio, L.M.E., Bado, P., Traore, I.M.A., Sama, W.A., Séni, N., Ouattara, A.K., Compaore, R.T., Bazié, V.J.T.E., Yelemkoure, T.E., Kiba, A., Yonli, A.T., Djigma, F. and Simpore, J.
Introduction: Hepatitis A virus (HAV) and hepatitis B virus (HBV) infections represent significant public health challenges in sub-Saharan Africa, including Burkina Faso. HAV is the most symptomatic viral hepatitis, while HBV is the most endemic and can lead to severe complications such as cirrhosis and hepatocellular carcinoma (HCC). HAV is a(...)
Hepatitis A Virus (HAV), Hepatitis B Virus (HBV), Seroprevalence, İmmunoglobulin (Ig), HBsAg, Burkina Faso
ARTICLE
Identification of Novel TERT Promoter Mutations in Chronic Hepatitis B-Induced HCC Patients in Burkina Faso
Zongo, V.S., Zhou, Y.M., Djigma, F.W., Roamba, E., Yonli, A.T., Sorgho, A.P., Barro, O., Somda, S.K., Compaore, T.R., Sanou, M., Martinson, J.J., Traore, L., Chamcheu, J.C., Zongo, J.K., Lompo, O.M., Roberts, L.R., Borad, M.J., Nagalo, B.M. and Simpore, J.K.
Introduction: Hepatocellular carcinoma (HCC) is one of the serious complications of chronic hepatitis B virus (HBV) infection and constitutes a major global public health problem. Several factors contribute to the development of this cancer, the genetic aspect of which is linked to mutations in genes such as the human telomerase reverse transc(...)
CHC, Chronic Hepatitis, Cirrhosis, TERT Promoter, Burkina Faso
ARTICLE
Agronomic Performance and Evaluation of Genetic Parameters of Okra Varieties [Abelmoschus esculentus (L.) Moench] in Diffa, Niger
IDI SAIDOU Sani, BACHIR ELHADJI BOUNOU Mandouwa, ABDOUL-KARIM TOUDOU Daouda, RABO Younoussou, MAHAMADOU Abdou, BACHIR ELHADJI BOUNOU Hadjara, ABDOU Laouali, RABIOU Abdou, MAHAMANE Ali, SAWADOGO Nerbéwendé? BAKASSO Yacoubou
Genetic parameter estimation is used to develop selection strategies for sustainable and climate smart agriculture. The aim of the study is to determine the level of agromorphological diversity and show which hereditary traits would have good heritability to be taken into account in varietal improvement and genetic progress. Seven hundred and(...)
Abelmoschus esculentus; genetic variability; heritability, morphological diversity; Niger.
ARTICLE
How do climate and land use affect structural attributes, diversity and carbon sequestration at both vegetation and species levels in West African savanna ecosystems?
Valaire Séraphin Ouehoudja Yaro, Loyapin Bondé, Pawend-taoré Christian Bougma, Reginald Tang Guuroh, Oumarou Ouédraogo & Anja Linstädter
Research on land use impacts on woody diversity and carbon stocks in West African savannas has primarily focused on the vegetation level. However, a combined analysis at both vegetation and species levels offers a more nuanced understanding of carbon loss patterns and provides stronger guidance for management and conservation of threatened spe(...)
Burkina Faso, Carbon dynamic, Land conversion, Species carbon, Woody diversity
ARTICLE
Influence of seed size and pretreatments on Faidherbia albida (apple‑ring) seed germination in Burkina Faso
Innocent Charles Emmanuel Traoré, Bossila Séraphin Hien, Valaire Séraphin Ouehoudja Yaro, Alhassane Zaré, Marie Louise Kaboré, Blaise Kabré, Loyapin Bondé & Oumarou Ouédraogo
Faidherbia albida (Delile) A. Chev. is a key agroforestry species that provides multiple ecosystem services, including soil fertilization, carbon sequestration, and forage production. Despite its ecological importance in climate change mitigation and its vital role for rural communities, natural populations of F. albida are declining due to po(...)
Dormancy, Germination percentage, Scarification, Seed category, Faidherbia albida, West Africa
ARTICLE
Acceptance, hesitancy, and ethical challenges of the COVID-19 vaccine in sub-Saharan Africa: a systematic review and meta-analysis
Denise P. Ilboudo, Abibou Simpore, Joseph Sawadogo, Abdoul Karim Ouattara, Alice R. Ouedraogo, Luc Zongo, Albert T. Yonli, Abdou Azaque Zoure, Theodora M. Zohoncon, Florencia W. Djigma, Dorcas Obiri-Yeboah, Charlemagne M. Ouedraogo, Jacques Simpore
Background: In light of the public health emergency brought about by the novel coronavirus, health authorities
actively promoted vaccination against SARS-CoV-2. The COVID-19 pandemic has brought to the forefront critical
questions concerning individual freedoms and the right to consent or decline vaccination. To better anticipate
and man(...)
COVID-19; vaccine; Acceptance; Hesitancy; Green pass; Ethic; Sub-Saharan Africa
ARTICLE
Molecular Detection of blaCTX-M-G1, blaVIM blaIMP and mcr Genes in Extended Spectrum β-Lactamase Bacilli Isolated at Schiphra Protestant Hospital, Ouagadougou, Burkina Faso
KJ. ZONGO, I. TIENDREBEOGO, MR. YOUGBARE, TWC. OUEDRAOGO, H. OUEDRAOGO, L. TRAORE, M. SAVADOGO, FW. DJIGMA and J. SIMPORE
Background and Aim: Infectious diseases nowadays are caused by multidrug-resistant bacteria,
making their management both difficult and costly. In Gram-negative bacilli, several enzymes
particularly ESBLs and carbapenemases allow to counteract the antibiotic effect of nearly all β
lactams. This leads to a dilemma for clinicians who increa(...)
Gram-negative bacilli; ESBL; Muitiplex PCR; CTX-M-1; IMP; VIM; mcr.
ARTICLE
INFLUENCE OF CLIMATIC, GENETIC AND IMMUNOLOGICAL FACTORS ON THE EVOLUTION OF DENGUE IN AFRICA: A REVIEW
Issoufou TAO, NIKIEMA Séni, Abdoul Karim OUATTARA, Koï Wenceslas KAM, Arsene Abakoudjiga MOUNGOU, Abdou Azaque ZOURÉ, Florencia W. DJIGMA, Bolni Marius NAGALO, Athanase BADOLO, Dorcas OBIRI-YEBOAH, Jacques SIMPORÉ
Over the past few decades, the incidence of dengue fever has increased dramatically worldwide, according to the World Health Organization (WHO). Several factors, including genetic, climatic, immunological and factors related to the virus (primarily Aedes aegypti and Aedes albopictus) and to humans,
are associated with the growing risk of the(...)
Africa, Dengue, Genetic, immunological and climatic factors, Review
ARTICLE
Anti-biofilm, anti-quorum sensing potential, cytotoxicity, and UPLC-UV/DAD-MS/MS/QTOF profiling of Prosopis Africana (Guill. & Perr.) Taub. leaves and stems extracts: benefits of a traditional medicine in dental care
Bance Alimata, Rouamba Ablassé, Compaoré Moussa, Compaoré Eli, Kabré W.M.E Leila, Ouedraogo Noufou, Hay A. Emmanuelle, Kiendrebeogo Martin & Dijoux-Franca Marie-Geneviève
Background
Prosopis africana is traditionally used in folk medicine in Burkina Faso for oral diseases. Leaves and stems are used in rural areas to treat dental caries, and the bark is used to treat green diarrhea in infants. In the context of a better understanding of Prosopis africana’s bioactivity and toxicity, the present study deals with(...)
Prosopis africana, UPLC-UV/DAD-ESI-MS/MS, Anti-biofilm, Anti-quorum sensing, Dental care, Polyphenols, Alkaloids
ARTICLE
Identification of Sources of Resistance in Cowpea [Vigna unguiculata (L.) Walp.] to Vascular Disease Caused by Fusarium solani in Burkina Faso
Kiswendsida Issaka Sam, Pawinde Elisabeth Zida, Benoit Joseph Batieno, Saadon Leandre Poda, Yannick Bassole, Abdou-kader Congo, Zakaria Dieni , Hamadou Zongo, Jean Baptiste Tignegre , Bouma James Neya, Nerbewende Sawadogo
Fusarium solani is a cosmopolitan fungus causing mortality of young cowpea plants and severe wilting at an advanced stage of plant development. As a result, it considerably affects cowpea production, undermining food and nutritional security. The use of resistant varieties combined with appropriate agricultural practices is a very effective an(...)
Burkina Faso; Fusarium solani; genotypes; resistance; Vigna unguiculata
ARTICLE
Assessment of Diversity in Parental and F1 Populations of Pearl Millet [Pennisetum glaucum (L.) R. Br.] in Burkina Faso
Lardia Ali BOUGMA, Adjima OUOBA, Dieudonné TARO, Nerbéwendé SAWADOGO
Aims: Pearl millet (Pennisetum glaucum (L.) R. Br.) is one of the cross-pollinated cereals in West Africa. It is cultivated for its grains. However, to date, strategies for selecting pearl millet populations and hybrids are low in West Africa. The objective of this study is to characterize the genetic bases of parental and F1 populations of pe(...)
Heterogeneity; F1 populations; genetic base; Burkina Faso; ICRISAT
ARTICLE
Evaluation of the biochemical and nutritional profiles of Solanum aethiopicum L. subsp Kumba fruits: implications for diet and health
Kayaba Kaboré , Crépin Ibingou Dibala , Mah Alima Esther Traoré , Roger Dakuyo , Adjaratou Souratié , Tienbnoma Sandrine Ouédraogo , Aïnattou Ouédraogo , Ouaro desiré , Jean Axel Tegwendé Kaboré , Kabakdé Kaboré , Hemayoro Sama , Mamounata Diao & Mamoudou Hama Dicko
African eggplant Solanum aethiopicum L. subsp., is an important vegetable crop in
tropical regions, particularly in Burkina Faso. The present study was initiated with the
aim of carrying out a biochemical characterization of its fruit called “Kumba”. The
macromolecule contents were determined by standard methods. The mineral contents
were(...)
Solanum aethiopicum; nutritional properties; amino acids; fatty acids; Burkina Faso
ARTICLE
Can permanganate oxidizable carbon, microbial respiration, and carbon mineralization rate reflect carbon dynamics across land use and pedo-climate gradients in West African semi-arid zones?
Gannouka Nadjire, Alimata Arzouma Bandaogo, Amanuel W. Gebremichael, Oumarou Ouédraogo and Joseph Issaka Boussim
Climate variability, soil type, land use, and vegetation structure modulate soil organic carbon (SOC) dynamics, but their effects on sensitive soil carbon indicators are not adequately quantified in semi-arid ecosystems. This research examined the independent and synergistic impacts of pedo-climate, land use, and canopy cover on permanganate o(...)
carbon dynamics, soil labile carbon, pedo-climatic conditions, dryland, microbial respiration, mineralization rates
ARTICLE
GC-MS characterization of bioactive compounds from Lippia multiflora Moldenke (Verbenaceae) flower essential oils and their antibiofilm potential against resistant bacteria
Ablassé Rouamba, Moussa Compaoré, Yahaya Zoungrana, Eli Compaoré & Martin Kiendrebeogo
Bacterial resistance to antibiotics is a global health challenge, partly due to biofilm formation, which protects bacteria against drugs and the immune system. This study investigated the potential of essential oils from Lippia multiflora flowers to inhibit bacterial biofilms, offering a natural alternative to address bacterial resistance. Ant(...)
Bacterial resistance, Biofilm, Essential oil, Lippia multiflora, Gas chromatography-mass spectrometry