Publications (155)
ARTICLE
Effects of supercritical carbon dioxide under conditions potentially conducive to sterilization on physicochemical characteristics of a liposome formulation containing apigenin
Kouka Luc Delma, Noémie Penoy, Bruno Grignard, Rasmané Semdé, Brigitte Evrard, Géraldine Piel
In this work, the effects of four supercritical carbon dioxide (ScCO2) conditions potentially conductive to sterilization,
on physicochemical characteristics of a liposome formulation containing apigenin (AG) were investigated.
These conditions were: C1 (ScCO2/70 ◦C/150 bar/240 min), C2 (ScCO2/0.25% water/ 0.15% H2O2)/
0.5% acetic anhydride(...)
Supercritical carbon dioxide, Liposomes, Sterilization, Physicochemical Characteristics
ARTICLE
Qualité rédactionnelle des prescriptions médicamenteuses au Centre Hospitalier Universitaire Yalgado OUEDRAOGO.
ENH YOUL, M Diop, H Zimé, M Ouédraogo, S Gampini, IP. Guissou
La prescription médicamenteuse contribue en grande partie au succès d’un acte médical. L’objectif de l’étude était d’évaluer la qualité des prescriptions médicamenteuses au CHU-YO.
Au cours de notre étude, 1201 ordonnances ont été analysées, 2940 médicaments ont été prescrits pour une moyenne de 2,45 médicaments par ordonnance avec 36,11 % de(...)
Qualité, Prescription, Évaluation, Médicament.
ARTICLE
Etude des constituants chimiques et activités antiradicalaires des extraits de huit plantes médicinales récoltées au mali
BALLO Mahamadou, YOUL Estelle N.H., HAIDARA Mahamane, DENOU Adama, BAH Sékou, OUEDRAOGO Moussa, SANOGO Rokia.
Les rôles potentiels des radicaux libres dans la pathogenèse de plusieurs maladies ont stimulé des recherches des composés antiradicalaires. L’objectif de cette étude était de doser des constituants chimiques et d’évaluer l’activité antiradicalaire des extraits de plantes utilisées dans le traitement traditionnel de l’inflammation et des infec(...)
Ximenia americana ; Terminalia macroptera ; Polyphénols totaux ; Activité anti-radicalaire ; Mali
ARTICLE
Etude des présentations des médicaments issus de la pharmacopée traditionnelle délivrés par les tradipraticiens de santé de la région sanitaire des cascades, Burkina Faso
Daniel Dori, Kikoun Paulin Camara, Siéssima Lawakilia Natacha Tchaida Martine Toe/Djiguimdé, Charles avouma Sombié, Hermine Zimé/Diawara, Boumbéwendin Gérard Josias Yameogo, Rasmané Semdé
Introduction : Le respect des exigences de présentation est l’une des conditions à l’octroi de l’autorisation de mise
sur le marché (AMM) des médicaments issus de la pharmacopée traditionnelle (MIPT). L’objectif de cette étude a
été d’évaluer les présentations des MIPT vendus par les tradipraticiens de santé (TPS) de la région sanitaire des(...)
forme galénique, étiquetage, conditionnement, médicaments issus de la pharmacopée traditionnelle
ARTICLE
Development of Tablets Based on Lannea Microcarpa Engl. Et K. Krause (Anacardiaceae) Extracts for Arterial Hypertension
Salfo Ouédraogo, Josias BG Yaméogo, Bavouma C. Sombié, Hermine Zime Diawara, Mathieu Nitiéma, Lazare Belemnaba, Tata Kadiatou Traoré, Sylvin Ouédraogo and Rasmané Semdé
act
In context of hypertension, research in African traditional medicine allows the identification of safe and effective recipes that lead to the development of phytomedicines or the isolation of molecules that can be used in managing of hypertensive patients.
Objectives: This study aims at formulating and evaluating tablets based on Lannea(...)
Arterial hypertension; Extracts; Formulations; Lannea macrocarpa; Tablets
ARTICLE
Capsule Formulation Essay of Herbal Extracts of Trunk Bark of Anogeissus leiocarpus (DC) Guill. Et Perr. (Combretaceae) for the Treatment of Hypertension
Ouedraogo Salfo, Sombie C. Bavouma, Diawara Zime Hermine, Yameogo B.G. Josias, Traore Tata Kadiatou, Nitiema Mathieu, Belemnaba Lazare, Ouedraogo Sylvin, Semde Rasmané
Introduction: The trunks barks of Anogeissus leiocarpus contains multiple antihypertensive components and are, therefore, widely used for the treatment of hypertension.
Objective: This study aimed to formulate capsules containing a freeze-dried aqueous extract of the trunk’s barks.
Methodology: Three (03) capsule formulations were prepared u(...)
Anogeissus leiocarpus, extract, excipients, formulations, capsule
ARTICLE
Development of capsule formulations containing freeze-dried aqueous extracts of Lannea microcarpa Engl. and K. Krause (Anacardiaceae)
Salfo Ouédraogo, Bavouma C. Sombié, Hermine Zime Diawara, Josias B.G. Yaméogo, Mathieu Nitiéma, Lazare Belemnaba, Tata Kadiatou Traoré, Sylvin Ouédraogo, Rasmané Semdé
Lyophilized powders of decocts of Lannea microcarpa have scientifically proven their efficacy and safety to treatment of arterial hypertension. However, these powders are very hygroscopic, with poor physicomechanical properties that cannot be used directly in capsules. Objective was to develop a capsule dosage form containing Lannea microcarpa(...)
Lannea microcarpa, capsules, medicinal plant, excipients, granules
ARTICLE
Sclerocarya birrea: Review of the pharmacology of its antidiabetic effects and toxicity.
Abdul Gafar Victoir Coulidiaty, Estelle Noëla Hoho YOUL, Téné Marceline Yaméogo
Sclerocarya birrea (A. Rich.) Hochst, an African widespread plant is known to be used for type 2 diabetes management in sub-Saharan Africa. This review aims to summarize the findings for the pharmacology of S. birrea antidiabetic effects and its in vivo and in vitro toxicity. To collate data on S. birrea, various scientific search engines like(...)
Sclerocarya birrea, type 2 diabetes, antidiabetic, toxicity.
ARTICLE
Preventive and Curative treatment of malaria during pregnancy in Mali: Evaluation of the Healthcare Professionals based on the Malian National Malaria Control Program (NMCP) Guidelines
Mahamadou Ballo, Karim Traoré, Sambou Sidibé, Seidina Diakité, Abdoulaye Guindo, Fatoumata Daou, Modibo Sangaré, Drissa Konaté, Mahamadou Diakité, YOUL Estelle, Sékou Bah
Malaria infections in pregnancy should be treated promptly with safe and efficacious antimalarial drugs to prevent harmful effects on the mother and fetus. To succeed, the Malian has developed NMCP guidelines for the management of malaria cases in pregnant women. The study aimed at the analysis of the prescription of antimalarial drugs based o(...)
Curative and Preventive Treatment, Malaria in Pregnancy, Malaria Transmission, Mali
ARTICLE
Research Article Contribution to the Detection of Poor Quality Sildenafil Drugs in Burkina Faso Using High-Performance Thin-Layer Chromatography
Abdoul Karim Sakira , Mit´eh´el´e Sandrine Marie Josiane Ouattara, Moussa Yabre , Moumouni Bande, and Touridomon Issa Some
Research Article
Contribution to the Detection of Poor Quality Sildenafil Drugs in
Burkina Faso Using High-Performance
Thin-Layer Chromatography
Abdoul Karim Sakira , Mit´eh´el´e Sandrine Marie Josiane Ouattara, Moussa Yabre ,
Moumouni Bande, and Touridomon Issa Some
Laboratoire de Toxicologie, Environnement et Sant´e (LATES), Ecole Doct(...)
Mots clés non renseignés
ARTICLE
Production de matières premières et fabrication des médicaments à base de plantes médicinales
Salfo OUEDRAOGO1*, Jules YODA, Tata Kadiatou TRAORE, Mathieu NITIEMA, Bavouma C. SOMBIE, Hermine Zime DIAWARA, Josias B.G. YAMEOGO, Abdoulaye DJANDE, Lazare BELEMNABA, Félix B. KINI, Sylvin OUEDRAOGO, Rasmané SEMDE
Les plantes constituent un réservoir pour les pharmacopées du monde. Plusieurs médicaments importants
sont fabriqués à partir des substances actives d’origine végétales. En outre de nombreux médicaments modernes
ont été fabriqués à partir de ces matières premières. Les plantes médicinales sont utilisées directement sous forme
fraîche, sèche(...)
Pharmacopée, médicaments, médecine traditionnelle, sécurité d’emploi, phytomédicaments.
ARTICLE
Pharmacological Evaluation of the Bronchorelaxant Effect of Waltheria indica L. (Malvaceae) Extracts on Rat Trachea
Rainatou Boly , Zakaline Yabre, Mathieu Nitiema , Boubacar Yaro, Jules Yoda, Lazare Belemnaba , Sylvain Ilboudo, Noëla Hoho Estelle Youl, Innocent Pierre Guissou, and Sylvin Ouedraogo
Waltheria indica L. (Malvaceae) is a plant used in Burkina Faso for the treatment of various ailments including asthma. The aim of the study was to evaluate the pharmacological relaxant effect of the leafy stem extracts of Waltheria indica and thereby verify claim of use in treating asthma. Aqueous decoction and hydroalcoholic extracts obtaine(...)
Bronchorelaxant effect, Waltheria indica L., Rat trachea
ARTICLE
Quality assessment of individual case safety reports in pharmacovigilance in Burkina Faso
Nazaire Roamba1,*, Emile Windné Ouedraogo3and Estelle Noella Hoho Youl2,4
Pharmacovigilance is based on individual case safety reports. Our study is intended to be a
contribution to good practices by the quality assessment of individual case safety reports sent to
the National Center for Vigilance in Burkina Faso. We carried out a cross-sectional study which
concerned individual case safety reports sent to the Ce(...)
Adverse effects, Drugs, WHO grade, Pharmacovigilance, Burkina Faso
ARTICLE
Study of manufacturing conditions of medicines derived from traditional pharmacopoeia in Benin and Burkina Faso
D. Dori, H.W.B. Ouedraogo, P.D. Houngue, F.A. Gbaguidi, B. Evrard, J. Quetin-Leclercq, R. Semdé
Introduction : La médecine traditionnelle est devenue un maillon important du système de soins des populations
africaines. De nombreux produits qui en sont issus sont de plus en plus utilisés dans l’arsenal thérapeutique. Ce travail fait l’état des lieux de la production de ces médicaments dans deux pays de l’Afrique de l’Ouest, le Burkina Fa(...)
Médecine traditionnelle; Pharmacopée traditionnelle ; Médicaments; Production; Matière première ; Burkina Faso ; Bénin
ARTICLE
Sterilization methods of liposomes: Drawbacks of conventional methods and perspectives
Kouka Luc Delma, Anna Lechanteur, Brigitte Evrard, Rasmané Semdé, Géraldine Piel
Liposomes are targeted drug delivery systems that are of great pharmaceutical and therapeutic interest.
Parenteral route is the main way used for liposome administration. In this case, their sterility is a requirement.
However, due to the particular sensitivity of liposomes and their tendency to physicochemical alterations, their
sterilizat(...)
Liposome, Sterilization, Conventional methods, Supercritical carbon dioxide