Publications (201)
ARTICLE
Cytochrome P450 2B6 6 distribution among patients living with HIV in Burkina Faso
Raoul KARFO , Fabienne Marie SOUDRE, Alice KIBA, Arnaud KOURAOGO, Elie KABRE, Jean SAKANDE
The function of cytochrome P450 (CYP) enzymes, one of the major catalysts in drug metabolism, is
significantly influenced by genetic polymorphisms leading to substantial inter-individual variability in drug
response and/ or adverse reactions activity. The aim of this study was to determine the frequency of the CYP2B6
516GT allele in pati(...)
CYP2B6 516 G>T, Correlation, clinical outcomes, HIV patients
ARTICLE
Phytochemical Analysis and Contractile Effects of Aqueous and Hydroethanolic Extracts of Anastatica hierochuntica L. (Brassicaceae) on the Isolated Uterus of Mice
Belem-Kabré Wendkouni Leila Marie Esther1*orcid, Nitiéma Mathieu1, Odjo Blondine Saïdath1, Maman Noura Oumarou1,2, Yaro Boubacar1, Kaboré Boukaré1,3, Somda Gaëtan Donzéo1, Traoré Tata Kadiatou1, Koala Moumouni1, Ilboudo Sylvain1, Ouédraogo Moussa2, Kabré Elie4, Ouédraogo Noufou1,2
Background: Anastatica hierochuntica L. (Brassicaceae) has been claimed to treat various conditions, including complicated childbirth. The principal objective of this research was to provide scientific evidence on the contractile effect of the aqueous and hydroethanolic extracts of the whole plant from A. hierochuntica during labor. Method: Qu(...)
PAnastatica hierochuntica, Phytoconstituents, Antioxidant, Anti-Inflammatory, Uterine Contractility
ARTICLE
Phytochemical Analysis and Contractile Effects of Aqueous and Hydroethanolic Extracts of Anastatica hierochuntica L.(Brassicaceae) on the Isolated Uterus of Mice
Belem-Kabré Wendkouni Leila Marie Esther, Nitiéma Mathieu, Odjo Blondine Saïdath, Maman Noura Oumarou, Yaro Boubacar, Kaboré Boukaré, Somda Gaëtan Donzéo, Traoré Tata Kadiatou, Koala Moumouni, Ilboudo Sylvain, Ouédraogo Moussa, Kabré Elie, Ouédraogo Noufou
Background: Anastatica hierochuntica L. (Brassicaceae) has been claimed to treat various conditions, including complicated childbirth. The principal objective of this research was to provide scientific evidence on the contractile effect of the aqueous and hydroethanolic extracts of the whole plant from A. hierochuntica during labor. Method: Qu(...)
Anastatica hierochuntica, Phytoconstituents, Antioxidant, Anti-Inflammatory
ARTICLE
EVALUATION DES BESOINS EN PREPARATIONS HOSPITALIERES OPHTALMIQUES DANS LES CENTRES HOSPITALIERS UNIVERSITAIRES DU BURKINA FASO
BC Sombié, SP Kambou, H Zimé-Diawara, J Sanou , M Ouédraogo, R Semdé
Introduction : au Burkina Faso, l’absence de médicaments de prédilection dans certaines pathologies oculaires entraine des difficultés dans leur prise en charge thérapeutique. L’objectif de notre travail était d’évaluer les
besoins en préparations hospitalières ophtalmologiques.
Méthodologie : une étude descriptive transversale a été réalisé(...)
kératites, conjonctivite chronique, collyre fortifié, abcès de la cornée, burkina Faso
ARTICLE
Evaluation in vitro de l’activité antiproliférative d’une crème à base de beurre de karité et de miel destinée à la prise en charge des plaies cancéreuses
Luc Zongo, Bagora Bayala, Charles Bavouma Sombié , Safiatou Traoré, Jacques Simporé, Rasmané Semdé
Certains types de cancer provoquent des plaies cancéreuses (PCs), créant inéluctablement un inconfort pour les malades et leurs soignants ; d’où la nécessité de la recherche de solutions endogènes pour leur traitement dans nos contrées. En effet, le miel, en plus de ses propriétés pharmacologiques connues, possède une cytotoxicité sélective ca(...)
beurre de karité – miel - activité antiproliférative - plaies cancéreuses
ARTICLE
Traditional uses, phytochemical and pharmacological properties of Feretia apodanthera Del. (Rubiaceae): a literature review
Gniènèfèrètien Nounaféri Awa Silué, Kampadilemba Ouoba, Francis Ngolsu, Salfo Ouedraogo, Gisèle Kouakou-Siransy, Rasmané Semdé
Traditional uses, phytochemical and pharmacological properties of Feretia apodanthera Del. (Rubiaceae): a literature review
Feretia apodanthera Del. (Rubiaceae), Traditional uses, phytochemical and pharmacological properties
ARTICLE
Assessment of pharmacy professionals’ knowledge and practice on the management and dispensing of investigational drugs in clinical trials
Grissoum Tarnagda, Moussa Ouedraogo, Bavouma Charles Sombié, Luc Kouka Delma , Eric Nagaonle Some, Jean Claude Romaric Pingwendé Ouédraogo, Olivier Sombié , Maxime K. Drabo and Rasmané Semdé
In quality approach for the development of clinical research in Africa, the level of knowledge and practices of professionals influences the quality of the trial, the confidence of the sponsors in the performance of sites. We evaluated the management and dispensing of experimental drugs in Burkina Faso. From January to June 2018, we conducted(...)
Pharmacy professional
ARTICLE
Evaluation of the physicochemical quality and antimicrobial performance of amoxicillin and amoxicillin + clavulanic acid discs used in Burkina Faso
Djibril Diallo, B. Gérard Josias Yaméogo, Ouéogo Nikiema, Mohamed Belem, W. Bertrand Goumbri, Belinda Mon´e Bassavé, Abdoul-Salam Ouédraogo, Elie Kabré, Rasmané Semdé
Antibiotic discs used in medical analysis laboratories are sourced from multiple manufacturers and suppliers and
must meet stringent quality requirements. This study aimed to assess the quality and performance of amoxicillin
and amoxicillin + clavulanic acid discs used in Burkina Faso. An evaluation of the use of antibiotic discs was
initia(...)
Antibiotic discs, Assay, Antimicrobial performance, Amoxicillin
ARTICLE
Subacute Toxicity, Subacute Anti-inflammatory and Anti-arthritic Activities of Combination of Hydroethanolic Extract of Terminalia macroptera and Ximenia americana In-vivo
Mahamadou Ballo, Filkpièrè Léonard Da, Sékou Bah, Rokia Sanogo and Estelle N. H. Youl
The aim of this study was to assess the anti-inflammatory effects of a combination of medicinal plants on two models of inflammation. Subacute toxicity was assessed by daily oral administration of 2000 mg/kg body weight (bw). Subacute inflammation and arthritis were induced using the carrageenan air pouch granuloma model and Complete Freund’s(...)
Terminaliamacroptera, Ximenia americana, Combination, Anti-inflammatory effect, Anti-arthritic effects, Oxidative stress
COMMUNICATION
Innovations galéniques et prise en charge des maladies infectieuses
YAMEOGO B. Gérard Josias
Les innovations galéniques constituent un élément fondamental du développement pharmaceutique.
Quand on évoque le sujet d’innovation galénique aujourd’hui, on pense à la nanotechnologie, une voie innovante pour véhiculer des molécules thérapeutiques vers une cible. En effet, de nombreuses substances actives présentent des caractéristiques phy(...)
Mots clés non renseignés
ARTICLE
Antiulcer Effect of Aqueous Ethanolic Extracts of Pseudocedrela kotschyi (Schweinf) Harms (Meliaceae) and Ximenia americana L. (Olacaceae)
Edwige T Delma, Moussa Ouédraogo, Aimé S Ouédraogo, Arsène W Nikiema, Moustapha Abdoulaye Gambo, Norbert Ramde, Estelle NH Youl, Assita Sanou-Lamien, Olga Mélanie Lompo, Pierre I Guissou
Purpose: This study aimed to provide pharmacological evidence of Pseudocedrela kotschyi and Ximenia americana in preventing or healing peptic ulcers claimed by traditional healers in Burkina Faso.
Methods: The trunk bark of Pseudocedrela kotschyi and the roots bark of Ximenia americana (Olacaceae) were macerated in mixed ethanol/ water (80:20(...)
Pseudocedrela kotschyi, Ximenia americana, Aqueous ethanolic extract, antiulcer, Antioxidant
ARTICLE
Preformulation study for the selection of a suitable polymer for the development of ellagic acid-based solid dispersion using hot-melt extrusion
Isaïe Nyamba, Olivier Jennotte , Charles B. Sombié , Anna Lechanteur , Pierre-Yves Sacre , Abdoulaye Djandé, Rasmané Semdé , Brigitte Evrard
Ellagic acid is one of the most studied polyphenolic compounds due to its numerous promising therapeutic properties. However, this therapeutic potential remains difficult to exploit owing to its low solubility and low permeability, resulting in low oral bioavailability. In order to allow an effective therapeutic application of EA, it is theref(...)
Ellagic acid, Polymers, Solid dispersions, Hot melt extrusion, Solubility
ARTICLE
Synergistic anti-inflammatory and analgesic activity of hydroethanolic extracts of Terminalia macroptera Guill. & Perr. and Ximenia americana L.
Mahamadou Ballo 1,*, Sékou Doumbia2, Daouda Dembelé, Raogo Ouedraogo, Estelle N. H. Youl, Rokia Sanogo, Sékou Bah
Inflammation is the reaction of the immune system to an external or internal aggression of the organism. The symptoms (redness, edema, heat and pain) are secondary to the increase in vascular permeability. The hydroethanolic extract of Terminalia macroptera and Ximenia americana has anti-inflammatory properties in vitro. The aim was to examine(...)
Terminalia macroptera, Ximenia americana, combinaison, Synergistic, Antiinflammatory
COMMUNICATION
Evaluation des produits cosmétiques capillaires et des pratiques de conseils en soins capillaires dans les officines de Ouagadougou.
H. Hermine G. ZIME-DIAWARA, B. Gérard Josias YAMEOGO, Ivette DABERE, Charles B. SOMBIE, N. Amina OUEDRAOGO, Rasmané SEMDE
4èmes Journées des Sciences de la Santé de l’UFR SDS (JSDS)
produits capillaires, cosmétiques, officines, états pelliculaires
ARTICLE
Evaluation des besoins en préparations hospitalières pédiatriques dans les Centres Hospitaliers Universitaires de Ouagadougou, Burkina Faso
Zimé Diawara Hermine, Sombié B. Charles, Yaméogo B.G. Josias, Bagaya Harouna, Delma Kouka Luc, Semdé Rasmané
Les préparations hospitalières, médicaments préparés au sein des hôpitaux, sont demandées principalement dans les spécialités pédiatrie et dermatologie. Il est rapporté par l’OMS, au sujet des médicaments, le problème de non disponibilité de formes galéniques pédiatriques pourtant utiles pour certains médicaments occasionnant ainsi des adminis(...)
Préparation hospitalière, pharmacie hospitalière, pédiatrie, centre hospitalier universitaire, médicaments