Publications (155)
ARTICLE
Formulation and In Vitro Release Studies of Emulgels Containing Shea Butter and Diclofenac Diethylamine
Hermine ZIME DIAWARA, Hyacinthe W. BONKOUGOU, Charles B. SOMBIE, Salfo OUEDRAOGO, Luc ZONGO, Josias B. G. YAMEOGO, Rasmané SEMDE
Shea butter is a raw material widely used in cosmetology. Its use in the pharmaceutical sector is becoming increasingly popular. As it’s commonly produced in Burkina Faso, it can help reduce medicine costs. Several dermatological formulations (creams, body milks, ointments) have been developed in our laboratories in Burkina Faso. However, some(...)
Diclofenac diethylamine, emulgel, shea butter, carbomer, arabic gum.
ARTICLE
Connaissances, attitudes et pratiques des tradipraticiens de santé dans la prise en charge de la dengue à Ouagadougou (Burkina Faso) en 2023
S. Traoré, H.G. Zime-Diawara, W.M. Yeo, F. Traoré, C.B. Sombie, D. Dori, T. Rouamba, N. Sawadogo, L. Zoungrana, R. Bognounou, H. Tiéno, O. Guira, R. Semdé
Introduction : Dans le contexte de l’émergence de la dengue au Burkina Faso, l’exploration des
alternatives thérapeutiques issues de la médecine traditionnelle pourrait permettre l’identification de
principes actifs à potentiel antiviral. Cette étude vise à documenter les connaissances, les attitudes et les
pratiques des tradipraticiens de(...)
connaissances ; attitudes ; pratiques ; dengue ; tradipraticiens de santé ; Burkina Faso
ARTICLE
Essais de formulation de crèmes et de pommades dermatologiques à base de beurre de karité raffiné et de dipropionate de betamethasone
Hermine Zime-Diawara, Charles Sombié, Salfo Ouédraogo, Marguerite Ouédraogo, Daniel Dori, Josias Yameogo, Rasmané Semdé
La production locale de médicaments avec des matières premières naturelles telles que le beurre de karité (BK) pourrait contribuer
à valoriser les ressources locales et à accroître l’arsenal thérapeutique en dermatologie. Cette étude avait pour but d’évaluer les
potentialités d’utilisation du BK raffiné comme excipient dans la fabrication de(...)
Beurre de karité, dipropionate de bétaméthasone, crème, pommade.
ARTICLE
Formulation and development of capsules containing dry extracts from the calyces of Hibiscus sabdariffa L. and the sheaths of Sorghum caudatum H., intended as a dietary supplement
Hermine ZIME DIAWARA, Mimtiri S. ZONGO, Ousseni SAWADOGO, Luc ZONGO, Salfo OUEDRAOGO, Modeste W. OUEDRAOGO, Heiko LANGE, Eloi PALE, Rasmane SEMDE
Introduction: Anthocyanin-rich extracts from Hibiscus sabdariffa L. calyces and Sorghum caudatum H. sheaths are promising antioxidants, but instability and dose variability limit use. This study aimed to standardize and manufacturing capsules containing lyophilized and purified dry extracts with affordable, plant-based excipients.
Methodology(...)
Hibiscus sabdariffa L., Sorghum caudatum H, anthocyanins, capsules
ARTICLE
In Vitro Evaluation of the Bioequivalence of Different Brands of Doxycycline Marketed in Burkina Faso, Africa
Bertrand Wendinmi Florent Goumbri, Annie Rebecca Bambara, Isaïe Nyamba, Wendpouiré Zoungrana-Somé , Bavouma Charles Sombié, Ouéogo Nikièma , Aïssata Sanfo-Diasso, Elie Kabré, Boumbéwendin Gérard Josias Yaméogo
Post-marketing quality control of drugs is an essential activity for local health authorities. This study aimed to determine the physicochemical quality and compare the dissolution profile of four different brands of doxycycline tablets (100 mg) (as hyclate and monohydrate forms) marketed in Burkina Faso, Africa. Methods: Parameters such as ma(...)
Doxycycline, physicochemical analysis, comparative dissolution, interchangeability
ARTICLE
Clay minerals used in formulations for cutaneous wound healing: An educational review
Paligwendé Anne Marie Kaboré , Raogo Ouédraogo, Bavouma Charles Sombié, Zakaline Yabré, Rasmané Semdé
In recent years, the use of clay minerals in wound treatment has been the subject of extensive researches. The present paper aimed to review studies on clay minerals-based formulations for the treatment of cutaneous wounds, highlighting the healing properties attributable to the addition of these minerals in formulations. A review of literatur(...)
Clays, Montmorillonite, Halloysite, Cutaneous wound, Healing
ARTICLE
Ethnobotanical Survey on Plants Used in the Treatment of Wounds by Traditional Health Practitioners in Burkina Faso
Safiatou Traoré, Hermine Diawara/Zimé, Salfo Ouédraogo, Souleymane Compaoré, Geoffroy Wendpanga Gasbeogo, Hyacinthe Wendégoudi Bonkoungou, Rasmané Semdé
Chronic wounds constitute a real problem in the sphere of care and
its management requires the mobilization of enormous financial resources
from the patient in low- and middle-income countries. In Burkina Faso,
traditional medicine has remained the most popular health care system.
However, very little data exists on the plants used specifi(...)
Plants; Healing; Traditional health practitioners; Burkina Faso
ARTICLE
Analyse du cadre légal et institutionnel des dispositifs medicaux dans les pays de l’UEMOA
Assitan KALOGA, Aboubacar SANGHO, Hermine ZIME DIAWARA, Rokia SANOGO, Rasmané SEMDE
Introduction : Les dispositifs médicaux (DM), à l’instar des médicaments, doivent être réglementés afin d’assurer leur efficacité
et leur sécurité d’emploi. L’objectif de ce travail était de décrire le cadre légal et institutionnel des DM dans les pays de l’UE-
MOA. Méthodologie : Il s’agissait d’une étude descriptive transversale qui s’est(...)
Dispositifs médicaux, Réglementation, Harmonisation, UEMOA
ARTICLE
Conception et Mise en Œuvre d'un Formulaire Thérapeutique au Centre Hospitalier Universitaire Pr Bocar Sidy Sall de Kati
Traoré Mohamed dit Sarmoye, Coulibaly Issa, Traoré Sylvestre, Traoré Mohamed, Traoré Abramane, Traoré Ousmane, Konaté Issa, Bengaly Loséni, Bah Sékou, Youl Estelle Noëla Hoho
Introduction. Le développement du formulaire thérapeutique consiste à préparer, utiliser et tenir à jour une liste des médicaments essentiels et des directives thérapeutiques standard pour un établissement de santé. Le but de cette étude était de développer un formulaire thérapeutique pour le CHU de Kati. Méthodologie. Le travail a été structu(...)
Conception, mise en œuvre, formulaire thérapeutique, Centre hospitalier Pr Bocar Sidy Sall de Kati (Mali)
ARTICLE
Effects of Crude Shea Butters and Their Polar Extracts on Singlet Oxygen Quenching and Against Rose Bengal-Induced HaCaT Cell Phototoxicity
Bertrand W. F. Goumbri , Olivia Jansen , Roland Marini Djang’eing’a , Michel Frederich , Rasmané Semdé , Touridomon Issa Somé , Sabine Danthine and Ange Mouithys-Mickalad ,*
Abstract: Shea butter (SB) is a raw material fat obtained from Vitellaria paradoxa C.F. Gaertn kernels. We investigated the direct and indirect protective effects of 10 traditional
and industrial SBs and their polar extracts on cell-free systems using ABTS and DPPH radical scavenging assays as well as on singlet oxygen (1O2) produced by Rose(...)
shea butter; phenol; antioxidant; singlet oxygen; photoprotection; HaCaT
ARTICLE
In Silico Inhibitory Potential of Isolated Molecules of Scoparia dulcis L. (Scrophulariaceae) on SARS-CoV-2 Main Protease Mpro
Ouedraogo, M. , Ouedraogo, W. , Yameogo, H. , Traore, I. , Boly, R. , Ouedraogo, N. , Semde, R. and Ouedraogo, S.
Background: The Coronavirus disease 2019 (COVID-19) pandemic, caused by the SARS-CoV-2 coronavirus, remains a global threat despite lifting the health emergency. Scientists from all continents have been mobilized to develop vaccines and medicines for prevention and cure. In Burkina Faso, traditional healers proposed using Scoparia dulcis L., a(...)
COVID-19, Molecular Docking, Mpro, Biomolecules, Scoparia dulcis
ARTICLE
In Silico Inhibitory Potential of Isolated Molecules of Scoparia dulcis L. (Scrophulariaceae) on SARS-CoV-2 Main Protease Mpro
Moussa Ouedraogo, Windbedema Prisca Ouedraogo, Hermann W. Yameogo, Inna T. Traore, Raïnatou Boly, Noufou Ouedraogo, Rasmané Semde, Sylvin Ouedraogo
Background: The Coronavirus disease 2019 (COVID-19) pandemic, caused
by the SARS-CoV-2 coronavirus, remains a global threat despite lifting the
health emergency. Scientists from all continents have been mobilized to develop
vaccines and medicines for prevention and cure. In Burkina Faso, traditional
healers proposed using Scoparia dulcis L(...)
COVID-19, Molecular Docking, Mpro, Biomolecules, Scoparia dulcis
ARTICLE
Characterization of medication errors in the Neonatology Unit of Teaching Pediatric Hospital of Ouagadougou, Burkina Faso
Moussa Ouedraogo, Guembre Adama, Emile W. Ouedraogo, Geoffroy W. Dibri, Charles B. Sombie, Aïssata Kabore and Kisito Nagalo
Medication errors were reported for the first time in 1962. Neonates are more exposed than other pediatric and adult patients. In Burkina Faso, a few medication errors in neonate care units are known.
This study aimed to characterize medication errors along the clinical medication circuit in the neonatology unit of the teaching pediatric hosp(...)
Medication errors, newborns, error characterization, Burkina Faso
ARTICLE
Medication Reconciliation at the Admission of the Medical Emergency Unit of Teaching Pediatric Hospital of Ouagadougou, Burkina Faso
Ouédraogo, M., Dibri, G.W., Ouédraogo, E.W., Ouoba, K., Adama, G., Sombie, C.B., Ouédraogo, A., Yoni, H., Kabore, A. and Youl, E.N.H.
Abstract
Introduction and Problem Statement: Many medication errors occur during
the community and hospital transition. Indeed, the World Health Organization
launched the international “High 5S” project to implement medication
reconciliation in healthcare facilities to reduce them and ensure patients a safe,
high-quality healthcare pathwa(...)
Admission Medication Reconciliation, Medication-Error, Medical Emergency Unit, Pediatric, Burkina Faso
ARTICLE
Contribution of clinical pharmacy to the rational and safe use of medicines in the neonatology unit of the pediatric university hospital Charles de Gaulle of Ouagadougou, Burkina Faso
Moussa Ouedraogo, Bonsdawindé Pagbelguem, Arsène Wendwaoga Nikiema, Charles B. Sombié, Emile W. Ouedraogo, Colette Zoungrana, Kisito Nagalo, Aïssata Kabore
Background: Newborns are exposed to drug therapeutic risks due to off-label prescribing and immaturity. The purpose of this study is to identify drug-related problems through the prescription and administration of drugs in the neonatology Unit and identify the need for pharmaceutical interventions.
Methods: To assess drug-related problems, a(...)
Neonatology, Drug-related problem, Medicines prescription and administration, Burkina Faso